Additionally, mRNA encoding other non-ATPase UPS subunits, including PSMD4 (p = 0.044), PSMD8 (p = 0.0032), and PSMD13 (p = 0.00022) also correlated with reduced OS in AML (Supplemental Figure S3A–C). The gene discussed is PSMD4; the disease is acute myeloid leukemia.