RPS6KA6 and acute myeloid leukemia: In contrast, RSK4 was identified as a tumour suppressor in other malignancies, such as colorectal and gastric cancers, as well as acute myeloid leukaemia (AML), where its overexpression induced cell cycle arrest, inhibited cell invasion and metastasis, and was associated with better patient survival [23,24,25,26,27].