Thus, we hypothesized that changing environmental conditions during healing after myocardial infarction, such as reduced inflammatory monocytes in the case of CCR2−/− mice or reduced neutrophil infiltration in the case of CCR1−/− mice, can have a significant influence on the synthesis of collagen subtypes, thus changing the composition of the scar and its mechanical properties. Here, CCR2 is linked to myocardial infarction.