Sestakova et al. analyzed previously-touted prognostic DNA methylation markers in AML across fourteen published studies, and confirmed methylation of four genes (CEBPA, PBX3, LZTS2, and NR6A1) as predictive for longer survival, as well as two other genes (DLX4 and GPX3) [101]. Here, LZTS2 is linked to acute myeloid leukemia.