NLRP3 and COVID-19: Here, we observed an increased NLRP3/ASC punctate structures formation in COVID-19/B.1 patients (Figure 3A; p < 0.0001 vs. control patients) and overexpressed in COVID-19/B1.1.7 patients (Figure 3A; p < 0.0001 vs. COVID-19/B.1 patients).