Therefore, various studies were conducted on the relationship between serum adiponectin concentrations and various diseases, such as type 2 diabetes (T2D), cardiovascular disease (CVD), cancer, polycystic ovary syndrome (PCOS), and cognitive dysfunction, but with conflicting results [6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23]. This evidence concerns the gene ADIPOQ and polycystic ovary syndrome.