ENG and hereditary hemorrhagic telangiectasia: Although bAVMs have a higher incidence in patients suffering from hereditary hemorrhagic telangiectasia, the endoglin expression observed in sporadic bAVMs was decreased in lesions obtained from patients with hereditary hemorrhagic telangiectasia, thus failing to prove a positive association between endoglin and the incidence of sporadic bAVMs [37,38,39,40].