Thus, high blood level of proinflammatory biomarkers, including IL-6, IL-8, and IL-15, can affect skeletal muscle mass and are suggestive of inflammation, whereas high blood level of anti-inflammatory biomarkers, i.e., IL-4, IL-10, and IL-15 can counteract the generation and activity of proinflammatory cytokines and consequently the muscle atrophy and sarcopenia [5,10,17,18,19,20,21,22]. Here, IL4 is linked to sarcopenia.