Actually, ORM1, or alpha-1 acid glycoprotein (AGP), which acts an acute response protein with multiple modulating activities, constitutes 1% to 3% of plasma proteins in humans and is mainly synthesized in the liver, has become a famous biomarker in many tumors such as lymphoma, bladder cancer, breast cancer, gastric cancer, as well as epithelial ovarian cancer [37,38,39,40,41]. This evidence concerns the gene ORM1 and urinary bladder cancer.