On the other hand, Evran et al. found no echocardiographic differences in five patients (mean age 49.60 ± 8.64 years) with adrenal ‘subclinical CS (SCS)’, defined based on non-suppressive cortisol level (>50 nmol/L) in post-DST results, and ACTH < 10 pg/mL as compared to 76 patients (mean age 52.09 ± 9.78 years) with nonfunctional adrenal incidentaloma (NFAI) [115]. The gene discussed is POMC; the disease is adrenal cortex adenoma.