POMC and Cowden syndrome 1: First, Muiesan et al. surveyed 42 patients with CS (36 with CD, 6 with adrenal adenoma, 1 each with adrenal carcinoma and ectopic ACTH production) and noted significantly larger LV interventricular septum diameter (IVSd) (10.1 ± 2.2 vs. 8.8 ± 1.3 mm, p = 0.05) and LV posterior wall diameter (PWd) (9.8 ± 1.7 vs. 7.8 ± 1.1 mm, p = 0.005) measurements as compared with control subjects matched for age, sex, body mass index (BMI), smoking habit, lipid level, BP level, and duration of hypertension [81].