The network analysis revealed potentially important hub genes, including DCN, IL33, VIM, VEGF, GPC4, KLF2, ELOVL5, KDM5A, Immunoglobulin, ZFP36, and the NF-κB, FOXO, and JAK/STAT signaling pathways that may be relevant to the pathophysiology of OHSS (Figure 2). This evidence concerns the gene GPC4 and ovarian hyperstimulation syndrome.