Concentrations of serum biomarkers (NT-proBNP and troponin) were significantly higher among DCM patients with MACE compared to children with DCM without MACE (NT-proBNP median 3068 vs. 58 pg/mL, troponin median 49 vs. 3 ng/mL) (Table 3). This evidence concerns the gene NPPB and familial dilated cardiomyopathy.