The authors presented 101,326 single-cell transcriptomes and surface protein profiles from the infusion products of 12 ALL patients, the results showed significant heterogeneity in antigen-specific activation states, with a deficiency of T helper 2 function associated with CD19-positive relapse vs. durable responders (remission, >54 months) [142]. Here, CD19 is linked to acute lymphoblastic leukemia.