Interleukin 6 (IL6, encoding IL-6) rs1800795 GC genotype was significantly more abundant in the CCA group than in the AFP+ or AFP− group (APF− vs. CCA, OR= 2.35, p < 0.05; APF+ vs. CCA, OR = 2.95, p < 0.05). The gene discussed is IL6; the disease is cholangiocarcinoma.