BRCA1 and neoplasm: Patients were categorized into five molecular profiles, consisting of (1) BRCAm profile (tumor BRCAm or BRCA1 promotor methylation), (2) non-BRCAmut HRD, (3) CCNE1 gain/amplification, (4) double classifier (non-BRCAmut HRD and CCNE1 gain/amplification), and (5) NSMP.