Similarly, in the 1999 study by Risch et al. [38], in which BRCA2 PVs were identified in 21 of 649 women with ovarian cancer, no association was found between risk of GC and presence of a BRCA2 PV (RR 2.3, 95% CI 0.30–18). This evidence concerns the gene BRCA2 and ovarian cancer.