BRCA2 and neoplasm: That same year, Jakubowska et al. [24] published a study based in Poland revealing that BRCA2 PVs were observed more frequently among 29 families with at least one female breast cancer diagnosed before the age of 50 and one male GC diagnosed before the age of 55 compared to 248 breast-ovarian cancer families (20.7% vs. 6.9%, p < 0.025).