ACAP1 and neoplasm: Pairwise comparisons between tumor and tumor-adjacent samples in the TCGA cohorts showed that ACAP1 expression was significantly lower in eight cancer types (BLCA, BRCA, COAD, KICH, LUSC, PRAD, THCA, and UCEC) but higher in four cancer types (CHOL, HNSC, KIRC, and STAD) (Figure 3B).