IL6 and cancer: Chronic, low-grade inflammation underpins many chronic illnesses such as cancer, as well as cardiovascular disease and type 2 diabetes, evidenced by elevations in levels of inflammatory biomarkers (e.g., C-reactive protein, interleukin 6 and 18, adhesion molecules (e.g., E selectin, intercellular adhesion molecule 1), vascular cell adhesion protein 1 and fibrinogen [104].