In our study, the significant upregulation of TRPV1 in GSCs vs. GBM cells (Figure 1C) and the cytotoxicity, presumably induced by TRPV1 antagonists CBD and CBG (Figure 6, Table 2) strongly supports the potential role of TRPV1 in GSC differentiation. The gene discussed is TRPV1; the disease is glioblastoma.