Our results showed that the signal was observed in B16F10 tumors of WT mice but not in CD11b−/− or CCR2−/− mice (B6.129S4-Ccr2tm1lfc/J) (Figure 3G), suggesting that the BG34-200 migration and distribution to tumor tissue was dependent on circulating cells that express inflammatory monocyte markers CD11b and CCR2. This evidence concerns the gene CCR2 and neoplasm.