Yet, TCGA dataset analysis via the University of Alabama at Birmingham CANcer data analysis Portal (UALCAN) [53] shows that only ACLY mRNA expression is significantly increased in tumor tissue compared with normal tissue (p = 2.81 × 10−6), whereas ACSS2 mRNA is expressed at reduced levels in tumors samples (p = 1.78 × 10−10) (Supplementary Figure S1B). This evidence concerns the gene ACSS2 and neoplasm.