One of the most widely used is the Memorial Sloan Kettering Cancer Center (MSKCC) colon cancer recurrence nomogram, which predicts freedom from recurrence based on nine clinicopathological features including age, tumor size, preoperative carcinoembryonic antigen (CEA), use of adjuvant chemotherapy, and other indicators of tumor invasiveness [6]. Here, CEACAM5 is linked to malignant colon neoplasm.