PDCD1 and Miyoshi myopathy: In dermatology, intravital microscopy has been used in a laboratory setting to better elucidate the mechanisms of resistance and ineffectiveness of immune and targeted therapies for MM, such as programmed cell death protein 1 (PD-1) and cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) blocking antibodies [121] and BRAF and mitogen-activated protein kinase (MEK) inhibitors [65].