AICDA and cancer: Figure 2 shows the top positively and negatively corrESB/IRSB enriched sets with p ≤ 10−3 after multiple hypotheses test correction for AID incidence (positive, Panel A; negative Panel B), for cancer incidence (positive, Panel C; negative Panel D), and their joint aggregate enrichment for both AID and cancer incidence (positive, Panel E, negative, Panel F).