When we performed a paired analysis with the corresponding normal tissues, a highly significant difference in H2O2 production was found in BRAF + TERT (p = 0.009), BRAF only (p = 0.003), ALL BRAF (p < 0.0001), RET or RAS mutated (p = 0.02), and ALL MUT tumors (p < 0.0001) but not in non-mutated PTCs (p = 0.12) (Figure 2, panel B). This evidence concerns the gene TERT and acute lymphoblastic leukemia.