IGF1R and breast cancer: The upregulated DEGs (VTCN1, KRT7, CD44, GATA3, ALOX15B, LRG1, RORC, NECTIN2, CD276, FOXM1 and IGF1R) (Supplementary Table S3 and Figure 2), include genes mainly expressed in BC cells and genes expressed both in BC and microenvironment cells [according to GeneCards® (RRID: SCR_002773)].