This compound induces apoptosis in human urothelial carcinoma cell lines, RT4 (WT TP53), HT-1197 (WT TP53), TCC-SUP (TP53 mutant), and T-24 (TP53 mutant), which is related to the control of several pro-apoptotic elements, including CASP3, CASP8, CASP9, PARP, BAX, and CDKN1A/p21, externalization of phosphatidylserine and DNA fragmentation. This evidence concerns the gene CDKN1A and urothelial carcinoma.