Neoalbaconol (14), a terpenoid isolated from the fungus Albatrellus confluens, targets PDPK1/PDK1 (3-phosphoinositide-dependent protein kinase 1) and inhibits the subsequent PI3K-AKT signaling in the nasopharyngeal carcinoma (NPC) nude mouse model, resulting in activation of autophagy [158]. This evidence concerns the gene PDK1 and nasopharyngeal carcinoma.