TP53 and colonic neoplasm: Ginsenoside compound K (22) enhances the pro-apoptotic impact of TNFRSF10A on colon cancer cells by inhibiting the expression of cell survival proteins, triggering expression of pro-apoptotic proteins (apoptosis regulator BAX, tBID and CYCS) and autophagy-dependent and autophagy-independent (TP53-DDIT3 pathway) upregulation of TNFRSF10B [173].