DDX53 and neoplasm: The experimental design for tumor challenge is shown in Figure 3A. The results of CT26-ROR1+ tumor challenge indicate that the mean tumor size in mice immunized with the TT peptide and Fc fragment containing fusion proteins (M17, H17/IFA and H17/CpG) was significantly less than that of the control group (p < 0.0001) (Figure 3B).