Although leukemia has not been recognized as a typical BRCA1/2-mutated cancer, our group and others have recently reported that certain types of leukemias and other hematopoietic malignancies display HR with/without concomitant c-NHEJ functional deficiency caused by leukemia-inducing mutations [18,23,24,25,26]. This evidence concerns the gene BRCA1 and leukemia.