Recent data showed that NEIL3 was overexpressed in various human cancers, including glioblastoma multiforme (GBM), breast cancer (BC), pancreatic adenocarcinoma (PADC), lung adenocarcinoma (LUAC), kidney renal clear cell carcinoma (KRCCC), kidney renal papillary cell carcinoma (KPCC) and low-grade glioma (LGG) [64]. This evidence concerns the gene NEIL3 and cancer.