We observed that tumor formation was inhibited in mice with knockdown of GOT1 expression compared with mice injected with exosomes alone, and representative images were shown in Figure 8A. In addition, we found that both the weight (Figure 8B) and volume (Figure 8C) of tumor tissues from mice with knockdown of GOT1 expression were much smaller than those from control group mice. This evidence concerns the gene GOT1 and neoplasm.