CD8A and adenocarcinoma: As shown in Figure 6B, the levels of dendritic cells (R = 0.61), macrophages (R = 0.56), neutrophils (R = 0.55), CD8+ (R = 0.32), and CD4+ (R = 0.31) T cells, as well as B cells (R = 0.10) infiltration, were positively correlated (p < 0.05) with the expression of ADGRF5 in the rectum of patients with adenocarcinoma.