Among distinct types of immune cells, the levels of dendritic cells (R = 0.62), macrophages (R = 0.56), neutrophils (R = 0.54), and CD4+ (R = 0.39), as well as CD8+ (R = 0.23) T cells infiltration were positively correlated (p < 0.05) with the expression of ADGRF5 in the colon of patients with adenocarcinoma (Figure 6A). This evidence concerns the gene CD4 and adenocarcinoma.