As a result, we found that cryptomeridiol (Bkh126; (1R,4aR,7R,8aR)-7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-2,3,4,5,6, 7,8,8a-octahydronaphthalen-1-ol; Figure 1A), a kind of sesquiterpenoid obtained from Magnolia officinalis, and some other sesquiterpenoid compounds, such as T7, obtained from marine P. indica, could strongly induce Nur77 expression in various HCC cells, including HepG2, Huh-7, and Hep3B (Figure 1B). Here, NR4A1 is linked to hepatocellular carcinoma.