Nevertheless, these theoretical analogies linking CEP55 with RNF157 require further experimentation, especially since the hydranencephaly of the MARCH syndrome is associated with a defect in the recruitment of CEP55 to the midbody [73]. This evidence concerns the gene CEP55 and multinucleated neurons-anhydramnios-renal dysplasia-cerebellar hypoplasia-hydranencephaly syndrome.