Breast cancer cells show high levels of LASP1 phosphorylated at S146 by PKA, while in chronic myeloid leukemia (CML) cells a dominant phosphorylation of LASP1 at Y171 by the constitutively active BCR-ABL tyrosine kinase was observed [11]. Here, LASP1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.