Owing to the promising association between SAPAP3 and OCD, much more attention has been given to Sapap3-mutant mice—a well-established OCD-relevant murine model displaying repetitive self-grooming behavior, augmented anxiety, cognitive inflexibility, imbalances between goal-directed and habitual behavior, selective deficits in behavioral response inhibition, insensitivity to reward devaluation, altered valence processing, hypolocomotion, disrupted sleep patterns, normal preference motivation for sucrose, and Pavlovian learning [13,102,104,106,157,158,159,160,161,162,163,164]. Here, DLGAP3 is linked to Anxiety.