A closer examination of the biological functions of the CanCord34 genes suggested that, although several of the CanCord34 genes have known functions in the process of oncogenesis (such as HSF1, GSDMD, EEF1D, MAF1, etc.), we noticed that the role of 13 of CanCord34 genes remains poorly understood in breast cancer. The gene discussed is HSF1; the disease is breast cancer.