Interestingly, because one of the co-overexpressed CanCord34 genes is MAPK15 (also referred to as ERK7 or ERK8), a commonly hyperactivated signaling kinase in breast and other human cancers [87,88], we postulate that MAPK15 overexpression can potentially create a positive loop between the persistent MAPK15 activation, the phosphorylation of its predicted nuclear substrates, and the upregulation of the target CanCord34 genes. This evidence concerns the gene MAPK15 and cancer.