Intriguingly, we observed how the OVA + STZ group enhanced protein expression in PI3K and mTOR levels, compared to the STZ group, which may explain why mice in the OVA + STZ group presented increased immune imbalance to Th2 humoral response to and showed increased susceptibility to diabetes when they were in a state of sensitization (Figure 7B,C). This evidence concerns the gene MTOR and diabetes mellitus.