Intriguingly, many of the genes have established links with kidney disease, including SLC27A2 (diabetic kidney disease)30, SLC3A1 (cystinuria), and GATM31; while others are associated with hypoxia (PHGD, CA12), inflammation (PPIA), and genotoxic stress (ASS1). This evidence concerns the gene SLC3A1 and diabetic kidney disease.