Role of UA in improving drug resistance in pancreatic cells was evaluated in another recent study, which showed that treatment with UA significantly lowered the levels of receptor for advanced glycation end products (RAGE), nuclear factor kappa B p65 (NF-κB/p65), and multidrug resistance protein 1 (MDR1) in pancreatic cancer cells. Here, ABCB1 is linked to pancreatic neoplasm.