PYCR1 and myocardial infarction: Using state‐of‐the‐art transcriptomic and metabolomic techniques, we found that Pycr1 gene KO affects unsaturated fatty acid metabolism at the transcriptional level, increasing the levels of metabolites such as fatty acids, glycerol phospholipids, and bile acids to play a protective role at the metabolic level in the heart after MI.