PYCR1 and coronary artery disorder: In particular, we observed an increase in phospholipid content in Pycr1 KO mice after MI, and recent studies have shown that phospholipid metabolism is quite strongly related to the occurrence and development of coronary heart disease; thus, phospholipid metabolism serves both as a novel diagnostic marker of MI and as a new therapeutic target.24, 25, 26, 27, 28, 29