According to the gene expressional differences between CD5Lhigh and CD5Llow HCC samples (Fig. 2A–B), 256 of the 1771 genes were higher (n = 122, Fig. 2C) or lower (n = 134, Fig. 2D) expressed in CD5Lhigh HCCs than the CD5Llow samples and they were CD5L-AGs. The gene discussed is CD5L; the disease is hepatocellular carcinoma.