MUC1 and idiopathic pulmonary fibrosis: Jiang et al., among 20 patients with IPF (no data on the proportion of patients with antifibrotic agents), also reported that the absolute changes in KL-6 levels within 1–6 months before disease evaluation were prognostic factors for DP (OR, 3.611; 95% CI 1.05–6.22; p < 0.01), which was defined as ≥ 10% absolute decline in FVC or ≥ 15% absolute decline in DLco from baseline over 12 months in the multivariate logistic analysis adjusted for by age, lung function, and disease extent as assessed using high-resolution computed tomography [18].