The CYP2E1 (also known as CPE1; CYP2E; P450-J; P450C2E) is located at 10q26.3 [30] and involved in drug metabolism and synthesis of cholesterol, steroids and other lipids, and is associated with gluconeogenesis, cancers, liver conditions, diabetes, SCZ, Parkinson’s disease, cognitive and neurobiological phenotypes [31–38]. Here, CYP2E1 is linked to diabetes mellitus.