Reduced mRNA levels of the genes FKRP and LARGE1, encoding fukutin-related protein and LARGE xylosyl- and glucuronyltransferase 1, respectively, have been reported in AML primary blasts (by ‒ 1.89 and ‒ 3.03, respectively), at variance with genes POMT1, POMT2 and POMGNT1, which were found overexpressed in cells of this tumor type (see above) [77]. The gene discussed is LARGE1; the disease is acute myeloid leukemia.