Other instances of LARGE1 mRNA downregulation were found in the glioblastoma cell lines U87MG, U251MG and LN-18 (by ‒ 6.67-fold) [106], in the leukemia cell lines HL-60 and Kasumi-1 (by ‒ 3.33-fold) [77], in the rhabdomyosarcoma cell lines Rh18 and others [96], and in the lung cancer cell lines H1299 and H2030 where it was almost undetectable [69]. The gene discussed is LARGE1; the disease is leukemia.