MYC and nonpapillary renal cell carcinoma: Subsequent rescue assays showed that overexpression of c-Myc or MARCKSL1 significantly rescued the inhibitory effects of circPLIN2 knockdown on the proliferation, migration, and invasion of ccRCC cells, suggesting that c-Myc and MARCKSL1 were involved in the circPLIN2-regulated development and progression of ccRCC.