NSG1 and neuropathy: Importantly, overexpression of NSG1 rescued neurite thinning in PtdIns(3,5)P2-deficient neurons, suggesting that NSG1 is downstream of PtdIns(3,5)P2 function and that activation of NSG1 function could serve as a new target for PtdIns(3,5)P2-related neuropathy.