CR – mouse (Hegab et al. 2019); mouse, breast cancer model (Pomatto-Watson et al. 2021); FMD – mouse, female (Brandhorst et al. 2015) ; IF – rat, myocardial infarct model (Wan et al. 2010); KD – mouse, COVID-19 model (Ryu et al. 2021); TF – mouse, male (Lettieri-Barbato et al. 2020); TRF – mouse, hypertension model (Sims et al. 2022). The gene discussed is TF; the disease is COVID-19.