t3, i3, ti3, v3, ptc3 cv3, g3, cg3, mm3, ci3, ct3, ah2, i-IFTA3, C4d0, t-IFTA2, ptcml3, pvl0, thrombotic microangiopathy, severe tubular damage. This evidence concerns the gene ZRANB3 and thrombotic microangiopathy.