In addition, further analysis using multivariate Cox regression model data showed that higher expression of ALDH1A1 was identified as an independent poorer prognostic factor for patients with NPC (P = 0.019), as well as metastasis, and advanced clinical stages (P = 0.001 and P = 0.011, respectively). This evidence concerns the gene ALDH1A1 and nasopharyngeal carcinoma.